After publishing a book exploring the evolution of the female body, Sara now considers further issues - will pornography lead to our extinction? Are humans naturally bad? How do we become better? Do we really have to die? and gulp, should she have a baby?
As always Sara is honest and unflinching as she expounds on sexuality, empathy, art, God and pubic hair. If that sounds a bit weighty, there will also be stuff about selfies, glow worms and RuPaul's Drag Race.
Sara has appeared on Live at the Apollo, Mock the Week, Have I Got News for You? QI, Room 101, Buzzcocks, 8 out of 10 Cats and a load of other programmes that can't be listed due to word count restrictions.
Sara's critically acclaimed book 'Animal: The Autobiography of a Female Body' (Faber & Faber) will be available to purchase with a signing after the show.