The Little Sisters of Hoboken discover that their cook, Sister Julia, Child of God, has accidentally poisoned 52 of the sisters. The remaining sisters decide that the best way to raise funds for the burials is to put on a variety show, so they take over the school auditorium, currently set up for Grease. We meet Reverend Mother Regina, a former circus performer, Sister Mary Huber, Mistress of Novices, streetwise nun Sister Robert Ann, Sister Mary Leo, a wannabe ballerina, and the delightfully wacky Sister Mary Amnesia, who lost her memory when a crucifix fell on her head!