When Rodolfo, a penniless poet, meets Mim�, a seamstress, they fall instantly in love. But their happiness is threatened when Rodolfo learns that Mim� is gravely ill.
Rodolfo is painfully aware that he cannot afford the medicine and care Mim� needs, and so separates from her. As her sickness takes hold Mim� returns to Rodolfo's garret. They are joyfully reunited - but, despite the care of Rodolfo and his friends, Mim� dies.